2022 American Athletic Conference Leaders Passes Defended - Games in December/January Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jarius Monroe | Tulane | JR | DB | 2 | 1 | 2 | 3 | 1.50 |
| 1 | Justin Hodges | UCF | JR | DB | 2 | 0 | 2 | 2 | 1.00 |
| 3 | Jayce Rogers | Houston | SR | DB | 1 | 1 | 1 | 2 | 2.00 |
| 3 | Divaad Wilson | UCF | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Jarvis Ware | UCF | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Arquon Bush | Cincinnati | SR | CB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Jalen Emery | Houston | FR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Abdul-Lateef Audu | Houston | JR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Art Green | Houston | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | AJ Davis | SMU | FR | CB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Matthew Peters | Navy | JR | CB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Donald Berniard Jr. | Navy | JR | NG | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Tre'Mon Morris-Brash | UCF | SR | DE | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Anthony Montalvo | UCF | SR | DT | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Ja'Cari Henderson | UCF | FR | DB | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Macon Clark | Tulane | SR | S | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Keith Cooper Jr. | Tulane | SO | DL | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Nick Anderson | Tulane | SR | LB | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Dorian Williams | Tulane | SR | LB | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Larry Brooks | Tulane | SR | S | 2 | 0 | 1 | 1 | 0.50 |