2022 American Athletic Conference Leaders Passing - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Clayton Tune | Houston | SR | QB | 1 | 33 | 22 | 66.7 | 208 | 6.3 | 2 | 0 | 139.62 | 33.0 | 208.0 |
| 2 | Seth Henigan | Memphis | SO | QB | 2 | 71 | 45 | 63.4 | 477 | 6.7 | 4 | 2 | 132.77 | 35.5 | 238.5 |
| 3 | Holton Ahlers | ECU | SR | QB | 1 | 51 | 32 | 62.7 | 288 | 5.6 | 1 | 2 | 108.81 | 51.0 | 288.0 |
| 4 | Tanner Mordecai | SMU | SR | QB | 2 | 98 | 59 | 60.2 | 670 | 6.8 | 4 | 4 | 122.94 | 49.0 | 335.0 |
| 5 | John Rhys Plumlee | UCF | SR | QB | 2 | 69 | 38 | 55.1 | 341 | 4.9 | 2 | 0 | 106.15 | 34.5 | 170.5 |
| 6 | Braylon Braxton | Tulsa | FR | QB | 1 | 25 | 13 | 52.0 | 146 | 5.8 | 1 | 0 | 114.26 | 25.0 | 146.0 |
| 7 | Michael Pratt | Tulane | JR | QB | 2 | 43 | 21 | 48.8 | 410 | 9.5 | 3 | 2 | 142.65 | 21.5 | 205.0 |
| 8 | Katravis Marsh | S Florida | SO | QB | 1 | 15 | 7 | 46.7 | 150 | 10.0 | 2 | 0 | 174.67 | 15.0 | 150.0 |
| 9 | Evan Prater | Cincinnati | SO | QB | 1 | 26 | 10 | 38.5 | 102 | 3.9 | 0 | 1 | 63.72 | 26.0 | 102.0 |
Note: To qualify, player must have played in 75% of his team's games and have a minimum of 15.0 pass attempts per game played.