2022 American Athletic Conference Leaders Interceptions - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Xavier Cullens | Memphis | SR | LB | 5 | 2 | 91 | 2 | 0.40 |
| 1 | Ja'Von Hicks | Cincinnati | SR | S | 5 | 2 | 64 | 1 | 0.40 |
| 1 | Jayce Rogers | Houston | SR | DB | 5 | 2 | 54 | 1 | 0.40 |
| 1 | Sylvonta Oliver | Memphis | SR | DB | 5 | 2 | 35 | 0 | 0.40 |
| 1 | Jarius Monroe | Tulane | JR | DB | 5 | 2 | 22 | 0 | 0.40 |
| 1 | Quindell Johnson | Memphis | SR | DB | 5 | 2 | 15 | 0 | 0.40 |
| 1 | Shanon Reid | SMU | SR | LB | 5 | 2 | 7 | 0 | 0.40 |
| 8 | Stephon Wright | SMU | JR | DT | 2 | 1 | 1 | 0 | 0.50 |
| 8 | Layton Jordan | Temple | JR | OLB | 4 | 1 | 41 | 1 | 0.25 |
| 8 | Dwayne Boyles | S Florida | SR | LB | 4 | 1 | 37 | 0 | 0.25 |
| 8 | Alex Odom | Temple | SO | SAF | 4 | 1 | 21 | 0 | 0.25 |
| 8 | Armorion Smith | Cincinnati | FR | S | 4 | 1 | 20 | 0 | 0.25 |
| 8 | Mekhi LaPointe | S Florida | SR | DB | 4 | 1 | 12 | 0 | 0.25 |
| 8 | Divaad Wilson | UCF | SR | DB | 4 | 1 | 0 | 0 | 0.25 |
| 8 | Jayden Curry | S Florida | SO | DB | 4 | 1 | 0 | 0 | 0.25 |
| 8 | Aamaris Brown | S Florida | FR | DB | 4 | 1 | 0 | 0 | 0.25 |
| 8 | Tyon Davis | Tulsa | SR | CB | 4 | 1 | 0 | 0 | 0.25 |
| 8 | Justin Wright | Tulsa | SR | LB | 4 | 1 | 0 | 0 | 0.25 |
| 8 | John Marshall | Navy | SR | STR | 4 | 1 | 0 | 0 | 0.25 |
| 8 | Jaylon Allen | Memphis | SR | DL | 5 | 1 | 39 | 1 | 0.20 |
| 8 | Art Green | Houston | SR | DB | 5 | 1 | 37 | 0 | 0.20 |
| 8 | Jireh Wilson | ECU | JR | SAF | 5 | 1 | 34 | 0 | 0.20 |
| 8 | Nelson Ceaser | Houston | SO | DL | 5 | 1 | 32 | 0 | 0.20 |
| 8 | Bryon Threats | Cincinnati | SO | S | 5 | 1 | 28 | 0 | 0.20 |
| 8 | Nick Roberts | SMU | SR | S | 5 | 1 | 27 | 0 | 0.20 |
| 8 | Gervarrius Owens | Houston | SR | DB | 5 | 1 | 24 | 0 | 0.20 |
| 8 | Thabo Mwaniki | Houston | SR | DB | 5 | 1 | 19 | 0 | 0.20 |
| 8 | Dorian Williams | Tulane | SR | LB | 5 | 1 | 13 | 0 | 0.20 |
| 8 | Chance Bates | ECU | SR | ILB | 5 | 1 | 11 | 0 | 0.20 |
| 8 | Taj Ward | Cincinnati | SR | CB | 5 | 1 | 4 | 0 | 0.20 |
| 8 | Arquon Bush | Cincinnati | SR | CB | 5 | 1 | 0 | 0 | 0.20 |
| 8 | Joel Williams | Memphis | SO | DB | 5 | 1 | 0 | 0 | 0.20 |
| 8 | Macon Clark | Tulane | SR | S | 5 | 1 | 0 | 0 | 0.20 |
| 8 | Corey Platt Jr. | Tulane | FR | LB | 5 | 1 | -1 | 0 | 0.20 |
| 8 | Julius Wood | ECU | JR | SAF | 5 | 1 | -2 | 0 | 0.20 |