2022 Atlantic Coast Conference Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Louisville | 4 | 43 | 42 | 9 | 94 | 23.5 |
| 2 | North Carolina | 3 | 26 | 34 | 10 | 70 | 23.3 |
| 3 | North Carolina State | 2 | 20 | 25 | 2 | 47 | 23.5 |
| 4 | Syracuse | 2 | 17 | 24 | 3 | 44 | 22.0 |
| 5 | Miami (Florida) | 2 | 21 | 23 | 6 | 50 | 25.0 |
| 5 | Duke | 2 | 20 | 23 | 4 | 47 | 23.5 |
| 5 | Wake Forest | 2 | 15 | 23 | 4 | 42 | 21.0 |
| 8 | Clemson | 2 | 22 | 19 | 5 | 46 | 23.0 |
| 9 | Virginia Tech | 2 | 21 | 16 | 1 | 38 | 19.0 |
| 10 | Boston College | 2 | 12 | 15 | 1 | 28 | 14.0 |
| 11 | Georgia Tech | 1 | 8 | 13 | 1 | 22 | 22.0 |
| 12 | Virginia | 1 | 12 | 11 | 3 | 26 | 26.0 |
| 13 | Florida State | 1 | 11 | 9 | 3 | 23 | 23.0 |
| 14 | Pittsburgh | 1 | 15 | 7 | 1 | 23 | 23.0 |