2022 Atlantic Coast Conference Leaders First Downs - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | North Carolina | 4 | 31 | 49 | 10 | 90 | 22.5 |
| 2 | Clemson | 4 | 38 | 41 | 11 | 90 | 22.5 |
| 3 | Georgia Tech | 4 | 24 | 33 | 4 | 61 | 15.3 |
| 4 | Wake Forest | 2 | 19 | 29 | 8 | 56 | 28.0 |
| 5 | Louisville | 3 | 22 | 28 | 4 | 54 | 18.0 |
| 6 | Florida State | 2 | 21 | 26 | 3 | 50 | 25.0 |
| 7 | Pittsburgh | 2 | 21 | 24 | 3 | 48 | 24.0 |
| 7 | Syracuse | 4 | 18 | 24 | 9 | 51 | 12.8 |
| 9 | Boston College | 3 | 14 | 23 | 3 | 40 | 13.3 |
| 10 | North Carolina State | 2 | 11 | 21 | 7 | 39 | 19.5 |
| 11 | Miami (Florida) | 3 | 16 | 17 | 5 | 38 | 12.7 |
| 12 | Virginia Tech | 1 | 7 | 10 | 4 | 21 | 21.0 |
| 12 | Duke | 1 | 7 | 10 | 1 | 18 | 18.0 |
| 14 | Virginia | 1 | 5 | 7 | 2 | 14 | 14.0 |