2022 Atlantic Coast Conference Leaders Scoring Defense - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 10 | 19 | 12 | 17 | 0 | 0 | 167 | 16.7 |
| 2 | Louisville | 10 | 20 | 11 | 20 | 0 | 0 | 173 | 17.3 |
| 3 | Virginia | 9 | 22 | 16 | 21 | 1 | 0 | 203 | 22.6 |
| 4 | Syracuse | 9 | 23 | 6 | 19 | 0 | 0 | 175 | 19.4 |
| 4 | Miami (Florida) | 9 | 23 | 11 | 23 | 0 | 0 | 194 | 21.6 |
| 6 | North Carolina State | 11 | 24 | 12 | 22 | 0 | 0 | 202 | 18.4 |
| 7 | Florida State | 11 | 25 | 12 | 23 | 1 | 0 | 211 | 19.2 |
| 7 | Virginia Tech | 10 | 25 | 18 | 21 | 0 | 1 | 227 | 22.7 |
| 7 | Georgia Tech | 8 | 25 | 9 | 22 | 1 | 0 | 201 | 25.1 |
| 10 | Pittsburgh | 11 | 30 | 14 | 25 | 0 | 0 | 247 | 22.5 |
| 10 | Boston College | 9 | 30 | 13 | 24 | 1 | 0 | 245 | 27.2 |
| 12 | Duke | 12 | 33 | 10 | 31 | 0 | 0 | 259 | 21.6 |
| 13 | Wake Forest | 11 | 36 | 15 | 29 | 2 | 1 | 296 | 26.9 |
| 14 | North Carolina | 10 | 39 | 8 | 35 | 1 | 0 | 295 | 29.5 |