2022 Atlantic Coast Conference Leaders Scoring Defense - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 5 | 6 | 6 | 6 | 0 | 0 | 60 | 12.0 |
| 2 | North Carolina State | 5 | 7 | 5 | 6 | 0 | 0 | 63 | 12.6 |
| 2 | Virginia | 3 | 7 | 2 | 7 | 0 | 0 | 55 | 18.3 |
| 4 | Virginia Tech | 4 | 8 | 8 | 8 | 0 | 1 | 82 | 20.5 |
| 5 | Miami (Florida) | 4 | 10 | 4 | 10 | 0 | 0 | 82 | 20.5 |
| 6 | Wake Forest | 5 | 11 | 6 | 8 | 2 | 1 | 98 | 19.6 |
| 6 | Boston College | 4 | 11 | 7 | 9 | 0 | 0 | 96 | 24.0 |
| 8 | Duke | 5 | 12 | 3 | 10 | 0 | 0 | 91 | 18.2 |
| 9 | Georgia Tech | 4 | 14 | 8 | 13 | 1 | 0 | 123 | 30.8 |
| 10 | Syracuse | 5 | 15 | 3 | 13 | 0 | 0 | 112 | 22.4 |
| 10 | Florida State | 5 | 15 | 4 | 13 | 1 | 0 | 117 | 23.4 |
| 12 | Clemson | 5 | 16 | 6 | 15 | 0 | 0 | 129 | 25.8 |
| 13 | Pittsburgh | 5 | 17 | 6 | 17 | 0 | 0 | 137 | 27.4 |
| 14 | North Carolina | 5 | 25 | 4 | 22 | 1 | 0 | 186 | 37.2 |