2022 Atlantic Coast Conference Leaders Rushing Defense - From Opponent's 21 To 39 Yard Line through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Virginia | 10 | 116 | 474 | 4.09 | 0 | 36 | 27 | 15 | 2 |
| 1 | Syracuse | 13 | 166 | 649 | 3.91 | 0 | 27 | 43 | 22 | 2 |
| 3 | Virginia Tech | 11 | 126 | 428 | 3.40 | 0 | 28 | 27 | 19 | 3 |
| 3 | Duke | 13 | 144 | 580 | 4.03 | 0 | 55 | 34 | 23 | 3 |
| 5 | North Carolina State | 13 | 125 | 360 | 2.88 | 0 | 39 | 13 | 12 | 4 |
| 5 | Miami (Florida) | 12 | 122 | 382 | 3.13 | 0 | 42 | 24 | 14 | 4 |
| 5 | Wake Forest | 13 | 158 | 470 | 2.97 | 0 | 25 | 34 | 23 | 4 |
| 5 | Clemson | 14 | 154 | 513 | 3.33 | 0 | 42 | 30 | 19 | 4 |
| 9 | Boston College | 12 | 120 | 562 | 4.68 | 1 | 65 | 23 | 20 | 5 |
| 9 | North Carolina | 14 | 168 | 811 | 4.83 | 2 | 74 | 44 | 18 | 5 |
| 11 | Pittsburgh | 13 | 127 | 553 | 4.35 | 1 | 63 | 24 | 18 | 7 |
| 11 | Florida State | 13 | 155 | 593 | 3.83 | 0 | 40 | 34 | 18 | 7 |
| 11 | Georgia Tech | 12 | 133 | 666 | 5.01 | 0 | 36 | 37 | 24 | 7 |
| 14 | Louisville | 13 | 155 | 584 | 3.77 | 0 | 46 | 34 | 25 | 9 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||