2022 Atlantic Coast Conference Leaders Long All Purpose Plays - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Zay Flowers | BC | SR | WR | 9 | 9 | 5 | 4 | 2 | 0 | 0 | 0 |
| 2 | Trey Benson | FSU | SO | RB | 11 | 10 | 4 | 1 | 1 | 1 | 1 | 1 |
| 2 | Jalon Calhoun | Duke | SR | WR | 12 | 9 | 4 | 1 | 0 | 0 | 0 | 0 |
| 2 | Key'Shawn Smith | Miami (Fl) | SO | WR | 8 | 6 | 4 | 3 | 3 | 3 | 1 | 1 |
| 2 | Jared Wayne | Pittsburgh | SR | WR | 10 | 8 | 4 | 3 | 2 | 0 | 0 | 0 |
| 2 | Johnny Wilson | FSU | SO | WR | 11 | 7 | 4 | 4 | 2 | 1 | 0 | 0 |
| 7 | Damien Alford | Syracuse | SO | WR | 9 | 4 | 3 | 1 | 0 | 0 | 0 | 0 |
| 7 | Lavel Davis Jr. | Virginia | JR | WR | 8 | 6 | 3 | 2 | 1 | 0 | 0 | 0 |
| 7 | Antoine Green | N Carolina | SR | WR | 6 | 4 | 3 | 2 | 0 | 0 | 0 | 0 |
| 7 | Sahmir Hagans | Duke | FR | WR | 12 | 5 | 3 | 1 | 1 | 1 | 1 | 0 |
| 7 | Tyler Hudson | Louisville | SR | WR | 9 | 5 | 3 | 0 | 0 | 0 | 0 | 0 |
| 7 | Jawhar Jordan | Louisville | SO | RB | 10 | 6 | 3 | 1 | 1 | 1 | 1 | 1 |
| 7 | Riley Leonard | Duke | SO | QB | 12 | 4 | 3 | 3 | 2 | 1 | 0 | 0 |
| 7 | Nate McCollum | Ga Tech | SO | WR | 7 | 3 | 3 | 1 | 0 | 0 | 0 | 0 |
| 7 | A.T. Perry | Wk Forest | JR | WR | 11 | 7 | 3 | 1 | 1 | 0 | 0 | 0 |
| 7 | Kaleb Smith | Va Tech | SR | WR | 10 | 5 | 3 | 2 | 1 | 1 | 1 | 0 |
| 7 | Ke'Shawn Williams | Wk Forest | SO | WR | 11 | 6 | 3 | 0 | 0 | 0 | 0 | 0 |
| 7 | Ontaria Wilson | FSU | SR | WR | 10 | 4 | 3 | 3 | 1 | 1 | 0 | 0 |
| 19 | Israel Abanikanda | Pittsburgh | JR | RB | 10 | 6 | 2 | 2 | 2 | 1 | 1 | 0 |
| 19 | LeQuint Allen | Syracuse | FR | RB | 9 | 3 | 2 | 1 | 1 | 1 | 1 | 1 |
| 19 | Brennan Armstrong | Virginia | SR | QB | 9 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 19 | Malachi Carter | Ga Tech | SR | WR | 7 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 19 | Malik Cunningham | Louisville | SR | QB | 7 | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| 19 | M.J. Devonshire | Pittsburgh | JR | DB | 10 | 4 | 2 | 2 | 1 | 1 | 1 | 0 |
| 19 | Tiyon Evans | Louisville | JR | RB | 7 | 3 | 2 | 2 | 1 | 1 | 0 | 0 |
| 19 | Elijah Green | N Carolina | SO | RB | 10 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 19 | Donavon Greene | Wk Forest | SO | WR | 11 | 6 | 2 | 1 | 1 | 0 | 0 | 0 |
| 19 | Jaquez Moore | Duke | SO | RB | 11 | 4 | 2 | 1 | 0 | 0 | 0 | 0 |
| 19 | Joseph Ngata | Clemson | SR | WR | 10 | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| 19 | Eli Pancol | Duke | SR | WR | 9 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 19 | Trebor Pena | Syracuse | SO | WR | 7 | 4 | 2 | 1 | 0 | 0 | 0 | 0 |
| 19 | Kentron Poitier | FSU | SO | WR | 11 | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| 19 | Will Shipley | Clemson | SO | RB | 10 | 4 | 2 | 2 | 0 | 0 | 0 | 0 |
| 19 | Brannon Spector | Clemson | JR | WR | 10 | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| 19 | Lawrance Toafili | FSU | SO | RB | 11 | 3 | 2 | 2 | 2 | 0 | 0 | 0 |
| 19 | Sean Tucker | Syracuse | SO | RB | 8 | 4 | 2 | 2 | 1 | 0 | 0 | 0 |
| 19 | Dontayvion Wicks | Virginia | JR | WR | 8 | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| 38 | D'Marcus Adams | Syracuse | JR | WR | 5 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | Davis Allen | Clemson | SR | TE | 10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | Kam Arnold | BC | JR | LB | 9 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | Jahmal Banks | Wk Forest | SO | WR | 10 | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | Cole Beck | Va Tech | SR | WR | 9 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | Jake Briningstool | Clemson | SO | TE | 10 | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | Alex Broome | BC | FR | RB | 8 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | Devin Carter | NC State | JR | WR | 7 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 38 | Kei'Trel Clark | Louisville | JR | DB | 9 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | Beaux Collins | Clemson | SO | WR | 7 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | John Copenhaver | N Carolina | SO | TE | 9 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| 38 | SirVocea Dennis | Pittsburgh | SR | LB | 11 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 38 | Brock Domann | Louisville | JR | QB | 8 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |