2022 Big 12 Conference Leaders Passes Defended - Games in December/January Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Texas Tech | 1 | 3 | 3 | 6 | 6.00 |
| 2 | TCU | 3 | 2 | 14 | 16 | 5.33 |
| 3 | Texas | 1 | 1 | 6 | 7 | 7.00 |
| 3 | Kansas | 1 | 1 | 5 | 6 | 6.00 |
| 3 | Kansas State | 2 | 1 | 5 | 6 | 3.00 |
| 3 | Oklahoma State | 1 | 1 | 4 | 5 | 5.00 |
| 3 | Oklahoma | 1 | 1 | 4 | 5 | 5.00 |