2022 Big 12 Conference Leaders Interceptions - Games in December/January Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Trey Rucker | Okla St | SR | S | 1 | 1 | 16 | 0 | 1.00 |
| 1 | Marquis Waters | Texas Tech | SR | DB | 1 | 1 | 11 | 0 | 1.00 |
| 1 | O.J. Burroughs | Kansas | SO | S | 1 | 1 | 0 | 0 | 1.00 |
| 1 | Billy Bowman Jr. | Oklahoma | SO | DB | 1 | 1 | 0 | 0 | 1.00 |
| 1 | Tyler Owens | Texas Tech | SR | DB | 1 | 1 | 0 | 0 | 1.00 |
| 1 | Dadrion Taylor-Demerson | Texas Tech | SR | DB | 1 | 1 | 0 | 0 | 1.00 |
| 1 | Jerrin Thompson | Texas | JR | DB | 1 | 1 | 0 | 0 | 1.00 |
| 1 | Julius Brents | Kansas St | SR | CB | 2 | 1 | 0 | 0 | 0.50 |
| 1 | Bud Clark | TCU | SO | S | 3 | 1 | 41 | 1 | 0.33 |
| 1 | Dee Winters | TCU | SR | LB | 3 | 1 | 29 | 1 | 0.33 |