2022 Big 12 Conference Leaders Interceptions - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Colby Reeder | Iowa State | SR | LB | 3 | 2 | 66 | 0 | 0.67 |
| 1 | Kobe Savage | Kansas St | JR | S | 3 | 2 | 0 | 0 | 0.67 |
| 1 | Cincere Mason | Kansas St | SR | S | 3 | 2 | 0 | 0 | 0.67 |
| 4 | Daniel Green | Kansas St | SR | LB | 4 | 2 | 50 | 0 | 0.50 |
| 5 | Josh Newton | TCU | JR | CB | 5 | 2 | 57 | 0 | 0.40 |
| 6 | Eriq Gilyard | Kansas | SR | LB | 3 | 1 | 11 | 0 | 0.33 |
| 6 | Reggie Pearson Jr. | Texas Tech | SR | DB | 3 | 1 | 11 | 0 | 0.33 |
| 6 | Anthony Johnson Jr. | Iowa State | SR | DB | 3 | 1 | 0 | 0 | 0.33 |
| 6 | Tyler Onyedim | Iowa State | FR | DL | 3 | 1 | 0 | 0 | 0.33 |
| 6 | Key Lawrence | Oklahoma | JR | DB | 3 | 1 | 0 | 0 | 0.33 |
| 6 | Gentry Williams | Oklahoma | FR | DB | 3 | 1 | 0 | 0 | 0.33 |
| 12 | D'Shawn Jamison | Texas | SR | DB | 4 | 1 | 69 | 1 | 0.25 |
| 12 | Jahdae Barron | Texas | JR | DB | 4 | 1 | 44 | 1 | 0.25 |
| 12 | Kenny Logan Jr. | Kansas | SR | S | 4 | 1 | 26 | 0 | 0.25 |
| 12 | Justin Harrington | Oklahoma | SR | DB | 4 | 1 | 22 | 0 | 0.25 |
| 12 | Marquis Waters | Texas Tech | SR | DB | 4 | 1 | 11 | 0 | 0.25 |
| 12 | Nick Allen | Kansas St | SR | LB | 4 | 1 | 2 | 0 | 0.25 |
| 12 | O.J. Burroughs | Kansas | SO | S | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Kendal Daniels | Okla St | FR | S | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Billy Bowman Jr. | Oklahoma | SO | DB | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Tyler Owens | Texas Tech | SR | DB | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Dadrion Taylor-Demerson | Texas Tech | SR | DB | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Jerrin Thompson | Texas | JR | DB | 4 | 1 | 0 | 0 | 0.25 |
| 24 | Dee Winters | TCU | SR | LB | 5 | 1 | 29 | 1 | 0.20 |
| 24 | Abe Camara | TCU | JR | S | 5 | 1 | 0 | 0 | 0.20 |
| 24 | Jaionte McMillan | TCU | SO | CB | 5 | 1 | 0 | 0 | 0.20 |
Note: To qualify, player must have played in 75% of his team's games.