2022 Conference USA Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | UAB | 11 | 130 | 88 | 24 | 242 | 22.0 |
| 2 | UTSA | 12 | 121 | 176 | 15 | 312 | 26.0 |
| 3 | North Texas | 13 | 115 | 142 | 16 | 273 | 21.0 |
| 4 | UTEP | 11 | 108 | 100 | 18 | 226 | 20.5 |
| 5 | Rice | 11 | 90 | 112 | 20 | 222 | 20.2 |
| 6 | Western Kentucky | 11 | 89 | 169 | 18 | 276 | 25.1 |
| 7 | Florida Atlantic | 10 | 81 | 106 | 24 | 211 | 21.1 |
| 8 | Florida International | 11 | 66 | 109 | 12 | 187 | 17.0 |
| 9 | Louisiana Tech | 9 | 65 | 90 | 20 | 175 | 19.4 |
| 10 | Charlotte | 9 | 59 | 111 | 18 | 188 | 20.9 |
| 10 | Middle Tennessee | 11 | 59 | 133 | 34 | 226 | 20.5 |