2022 Conference USA Leaders First Downs - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | UTSA | 2 | 16 | 29 | 4 | 49 | 24.5 |
| 2 | Western Kentucky | 1 | 8 | 17 | 3 | 28 | 28.0 |
| 3 | Rice | 1 | 6 | 7 | 1 | 14 | 14.0 |
| 4 | Charlotte | 1 | 4 | 13 | 4 | 21 | 21.0 |
| 5 | UAB | 1 | 3 | 8 | 1 | 12 | 12.0 |
| 6 | Louisiana Tech | 1 | 2 | 10 | 2 | 14 | 14.0 |