2022 Conference USA Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Middle Tennessee | 1 | 2 | 6 | 8 | 8.00 |
| 1 | Charlotte | 2 | 2 | 1 | 3 | 1.50 |
| 3 | Louisiana Tech | 2 | 1 | 8 | 9 | 4.50 |
| 3 | Florida Atlantic | 1 | 1 | 1 | 2 | 2.00 |
| 5 | Western Kentucky | 2 | 0 | 10 | 10 | 5.00 |
| 5 | UAB | 1 | 0 | 3 | 3 | 3.00 |
| 5 | UTEP | 1 | 0 | 3 | 3 | 3.00 |
| 5 | UTSA | 1 | 0 | 1 | 1 | 1.00 |