2022 Conference USA Leaders Total Offense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 2 | 301 | 629 | 169 | 930 | 5.50 | 465.0 |
| 2 | Charlotte | 2 | 175 | 505 | 144 | 680 | 4.72 | 340.0 |
| 3 | Louisiana Tech | 2 | 14 | 647 | 131 | 661 | 5.05 | 330.5 |
| 4 | Middle Tennessee | 1 | 99 | 408 | 61 | 507 | 8.31 | 507.0 |
| 5 | Florida Atlantic | 1 | 189 | 230 | 73 | 419 | 5.74 | 419.0 |
| 6 | UTSA | 1 | 139 | 269 | 84 | 408 | 4.86 | 408.0 |
| 7 | UTEP | 1 | 28 | 288 | 82 | 316 | 3.85 | 316.0 |
| 8 | Rice | 1 | 146 | 134 | 62 | 280 | 4.52 | 280.0 |
| 9 | UAB | 1 | 48 | 211 | 57 | 259 | 4.54 | 259.0 |