2022 Conference USA Leaders Opponent First Downs - Games vs. Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | North Texas | 9 | 89 | 111 | 10 | 210 | 23.3 |
| 2 | Middle Tennessee | 8 | 58 | 108 | 11 | 177 | 22.1 |
| 3 | Florida Atlantic | 8 | 64 | 81 | 12 | 157 | 19.6 |
| 4 | UAB | 8 | 63 | 73 | 13 | 149 | 18.6 |
| 5 | UTEP | 8 | 53 | 88 | 14 | 155 | 19.4 |
| 5 | Western Kentucky | 8 | 64 | 88 | 14 | 166 | 20.8 |
| 7 | UTSA | 9 | 65 | 98 | 15 | 178 | 19.8 |
| 7 | Charlotte | 8 | 79 | 85 | 15 | 179 | 22.4 |
| 9 | Rice | 8 | 65 | 74 | 16 | 155 | 19.4 |
| 10 | Louisiana Tech | 8 | 88 | 89 | 19 | 196 | 24.5 |
| 11 | Florida International | 8 | 84 | 102 | 21 | 207 | 25.9 |