2022 Conference USA Leaders Passes Defended - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Wayne Jones | Charlotte | JR | DB | 1 | 1 | 1 | 2 | 2.00 |
| 1 | Starling Thomas V | UAB | SR | CB | 1 | 0 | 2 | 2 | 2.00 |
| 3 | Derrick Smith | Western Ky | SR | LB | 1 | 1 | 0 | 1 | 1.00 |
| 3 | Drew Tuazama | UAB | JR | DL | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Willie Roberts | La Tech | JR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Tyler Grubbs | La Tech | SO | LB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Khiry Morrison | La Tech | SO | LB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Reginald Johnson Jr. | La Tech | SO | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Will Ignont | Western Ky | SR | LB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Clifford Chattman | UTSA | SR | S | 2 | 1 | 0 | 1 | 0.50 |
| 3 | Kelechi Nwachuku | UTSA | SR | S | 2 | 1 | 0 | 1 | 0.50 |
| 3 | Trey Moore | UTSA | FR | OLB | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Ken Robinson | UTSA | JR | CB | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Corey Mayfield Jr. | UTSA | SR | CB | 2 | 0 | 1 | 1 | 0.50 |
| 3 | Asyrus Simon | UTSA | JR | DL | 2 | 0 | 1 | 1 | 0.50 |