2021 Louisville Cardinals Penalty Split Stats through 01/10/2022
| Split | G | Pen. | Yards | Pen./G | Yards/G |
|---|---|---|---|---|---|
| All Games | 13 | 80 | 714 | 6.2 | 54.9 |
| at Home | 7 | 36 | 310 | 5.1 | 44.3 |
| on Road/Neutral Site | 6 | 44 | 404 | 7.3 | 67.3 |
| in Wins | 6 | 34 | 320 | 5.7 | 53.3 |
| in Losses | 7 | 46 | 394 | 6.6 | 56.3 |
| vs. Conference | 8 | 55 | 499 | 6.9 | 62.4 |
| vs. Non-Conference | 5 | 25 | 215 | 5.0 | 43.0 |
| vs. Ranked (AP) | 5 | 37 | 313 | 7.4 | 62.6 |
| vs. Unranked (AP) | 8 | 43 | 401 | 5.4 | 50.1 |
| vs. FBS (I-A) | 12 | 74 | 673 | 6.2 | 56.1 |
| vs. FCS (I-AA) | 1 | 6 | 41 | 6.0 | 41.0 |
| vs. FBS Winning | 7 | 44 | 389 | 6.3 | 55.6 |
| vs. FBS Non-Winning | 5 | 30 | 284 | 6.0 | 56.8 |
| vs. FBS Power 5 | 10 | 67 | 597 | 6.7 | 59.7 |
| vs. FBS non-Power 5 | 2 | 7 | 76 | 3.5 | 38.0 |
| in August/September | 4 | 26 | 242 | 6.5 | 60.5 |
| in October | 4 | 31 | 283 | 7.8 | 70.8 |
| in November | 4 | 20 | 159 | 5.0 | 39.8 |
| in December/January | 1 | 3 | 30 | 3.0 | 30.0 |