2021 National Leaders Passes Defended - Games in November Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Marcus Jones | Houston | SR | CB | 4 | 4 | 9 | 13 | 3.25 |
| 2 | Donte Kent | CMU | FR | DB | 4 | 0 | 8 | 8 | 2.00 |
| 3 | Steven Jones Jr. | App St | SR | DB | 4 | 3 | 4 | 7 | 1.75 |
| 3 | Dane Belton | Iowa | JR | DB | 4 | 3 | 4 | 7 | 1.75 |
| 3 | Quindell Johnson | Memphis | JR | DB | 4 | 1 | 6 | 7 | 1.75 |
| 3 | Samuel Womack | Toledo | SR | CB | 4 | 0 | 7 | 7 | 1.75 |
| 3 | Charles Amankwaa | Akron | JR | DB | 4 | 0 | 7 | 7 | 1.75 |
| 3 | Starling Thomas V | UAB | JR | CB | 4 | 0 | 7 | 7 | 1.75 |
| 9 | Andrew Booth Jr. | Clemson | JR | CB | 3 | 3 | 3 | 6 | 2.00 |
| 9 | TieNeal Martin | Tulsa | SR | S | 4 | 3 | 3 | 6 | 1.50 |
| 9 | Cam Smith | S Carolina | SO | DB | 4 | 3 | 3 | 6 | 1.50 |
| 9 | Jacobi Francis | Memphis | SR | DB | 4 | 2 | 4 | 6 | 1.50 |
| 9 | Russ Yeast | Kansas St | SR | DB | 4 | 1 | 5 | 6 | 1.50 |
| 9 | Natrone Brooks | USM | JR | DB | 4 | 1 | 5 | 6 | 1.50 |
| 9 | DJ Turner | Michigan | JR | DB | 4 | 1 | 5 | 6 | 1.50 |
| 9 | Tre Bugg III | Air Force | SR | DB | 4 | 1 | 5 | 6 | 1.50 |
| 9 | Jakorian Bennett | Maryland | SR | DB | 4 | 1 | 5 | 6 | 1.50 |
| 9 | Roger McCreary | Auburn | SR | CB | 4 | 0 | 6 | 6 | 1.50 |
| 9 | Kenneth Harris | Ark St | FR | CB | 4 | 0 | 6 | 6 | 1.50 |
| 20 | Dy'vonne Inyang | UTEP | SR | DB | 2 | 1 | 4 | 5 | 2.50 |
| 20 | Bryquice Brown | Georgia St | SO | CB | 3 | 2 | 3 | 5 | 1.67 |
| 20 | Montre Miller | Kent State | JR | CB | 3 | 1 | 4 | 5 | 1.67 |
| 20 | DaRon Bland | Fresno St | SR | DB | 3 | 1 | 4 | 5 | 1.67 |
| 20 | Lu-Magia Hearns III | California | FR | CB | 3 | 1 | 4 | 5 | 1.67 |
| 20 | Bobby Brown, II | SJSU | SR | DB | 3 | 0 | 5 | 5 | 1.67 |
| 20 | Antavious Lane | Georgia St | SO | S | 4 | 3 | 2 | 5 | 1.25 |
| 20 | Mark Perry | Colorado | SO | S | 4 | 2 | 3 | 5 | 1.25 |
| 20 | Derrek Pitts, Jr. | NC State | SR | CB | 4 | 2 | 3 | 5 | 1.25 |
| 20 | Al Walcott | Baylor | JR | CB | 4 | 2 | 3 | 5 | 1.25 |
| 20 | Grayson Cash | UAB | JR | S | 4 | 2 | 3 | 5 | 1.25 |
| 20 | Montaric Brown | Arkansas | SR | DB | 4 | 2 | 3 | 5 | 1.25 |
| 20 | Caesar Williams | Wisconsin | SR | CB | 4 | 2 | 3 | 5 | 1.25 |
| 20 | Jaylon Jones | Texas A&M | SO | DB | 4 | 1 | 4 | 5 | 1.25 |
| 20 | Theo Jackson | Tennessee | SR | DB | 4 | 1 | 4 | 5 | 1.25 |
| 20 | Kaonohi Kaniho | Boise St | FR | CB | 4 | 1 | 4 | 5 | 1.25 |
| 20 | Omarion Cooper | FSU | FR | DB | 4 | 1 | 4 | 5 | 1.25 |
| 20 | Jabari Moore | Army | SO | CB | 4 | 1 | 4 | 5 | 1.25 |
| 20 | Jaylon Monroe | Tulane | SR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Corey Thornton | UCF | SO | DB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Steven Gilmore | Marshall | JR | DB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Sean Fresch | Rice | FR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Darrell Baker Jr. | Ga South | SR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Jahari Rogers | SMU | FR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Josh Wallace | U Mass | SO | CB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Jaylin Williams | Indiana | SR | DB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Denzel Burke | Ohio State | FR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Darius Rush | S Carolina | JR | DB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Tre'Vius Hodges-Tomlinson | TCU | JR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 20 | Cole Godbout | Wyoming | JR | NT | 4 | 0 | 5 | 5 | 1.25 |
| 50 | Mark Lee Jr. | EMU | FR | DB | 2 | 0 | 4 | 4 | 2.00 |
| 50 | Xavion Alford | USC | FR | S | 3 | 3 | 1 | 4 | 1.33 |
| 50 | Deshawn Jones Jr. | BGSU | FR | CB | 3 | 3 | 1 | 4 | 1.33 |
| 50 | Quavian White | Georgia St | SR | CB | 3 | 1 | 3 | 4 | 1.33 |
| 50 | Dallas Branch | SDSU | JR | CB | 3 | 1 | 3 | 4 | 1.33 |
| 50 | Darian Chestnut | Syracuse | FR | DB | 3 | 1 | 3 | 4 | 1.33 |
| 50 | Colin Schooler | Texas Tech | SR | LB | 3 | 1 | 3 | 4 | 1.33 |
| 50 | Kaleb Hayes | BYU | JR | DB | 3 | 0 | 4 | 4 | 1.33 |
| 50 | Aapri Washington | Buffalo | SR | CB | 3 | 0 | 4 | 4 | 1.33 |
| 50 | DaMarcus Fields | Texas Tech | SR | DB | 3 | 0 | 4 | 4 | 1.33 |
| 50 | AJ Finley | Miss | JR | DB | 4 | 3 | 1 | 4 | 1.00 |
| 50 | Beanie Bishop | Western Ky | SO | DB | 4 | 3 | 1 | 4 | 1.00 |
| 50 | Omari Alexander | Western Ky | SR | DB | 4 | 3 | 1 | 4 | 1.00 |
| 50 | Ricky Johnson | UNLV | SO | DB | 4 | 3 | 1 | 4 | 1.00 |
| 50 | Joe Joe Headen | ODU | SR | S | 4 | 2 | 2 | 4 | 1.00 |
| 50 | Gabe Taylor | Rice | FR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 50 | Cam'Ron Kelly | N Carolina | JR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 50 | Davion Williams | Western Ky | SO | DB | 4 | 2 | 2 | 4 | 1.00 |
| 50 | Kahlef Hailassie | Western Ky | SO | DB | 4 | 2 | 2 | 4 | 1.00 |
| 50 | Alex Spillum | Coast Car | SR | S | 4 | 2 | 2 | 4 | 1.00 |
| 50 | Patrick McMorris | SDSU | JR | S | 4 | 2 | 2 | 4 | 1.00 |
| 50 | Warren Saba | ECU | SR | SAF | 4 | 2 | 2 | 4 | 1.00 |
| 50 | J.T. Wahee | Ball State | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Roman Parodie | Ohio | FR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Troy Brown | CMU | JR | LB | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Dorian Strong | Va Tech | FR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Quincy Riley | MTSU | FR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Kyle Soelle | Ariz St | SR | LB | 4 | 1 | 3 | 4 | 1.00 |
| 50 | DeAndre Pierce | Ariz St | SR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Shyheim Battle | NC State | FR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Myles Slusher | Arkansas | SO | DB | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Scott Nelson | Wisconsin | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 50 | Quinyon Mitchell | Toledo | FR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | A.J. Thomas | W Mich | SR | LB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Elvis Hines | Kent State | SR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Jaylon Jones | Georgia St | SR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | CJ Burton | BC | FR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Cole Bishop | Utah | FR | S | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Micah Abraham | Marshall | SO | DB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Jordan Helm | FAU | SR | S | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Tyreek Chappell | Texas A&M | FR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Zakoby McClain | Auburn | SR | LB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Roger Cray | ODU | SR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Myjai Sanders | Cincinnati | SR | DL | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Jordan Dunbar | Rice | FR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Warren Burrell | Tennessee | JR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Syrus Dumas | NMSU | SO | DB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Decorian Patterson | MTSU | SO | CB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Kordell Rodgers | Texas St | JR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Torey Richardson | UTEP | SO | CB | 4 | 0 | 4 | 4 | 1.00 |
| 50 | Cortez Davis | Hawai'i | SR | DB | 4 | 0 | 4 | 4 | 1.00 |