2021 FBS Independents Leaders Tackles For Loss - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Notre Dame | 10 | 64.0 | 319 | 6.40 |
| 2 | BYU | 7 | 26.0 | 124 | 3.71 |
| 3 | New Mexico State | 2 | 12.0 | 53 | 6.00 |
| 4 | Connecticut | 3 | 17.0 | 51 | 5.67 |
| 5 | Liberty | 2 | 14.0 | 47 | 7.00 |
| 6 | Army | 3 | 14.0 | 43 | 4.67 |
| 7 | Massachusetts | 3 | 10.0 | 34 | 3.33 |