2021 Independent Leaders Total Offense - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Notre Dame | 10 | 1506 | 2818 | 693 | 4324 | 6.24 | 432.4 |
| 2 | BYU | 7 | 1394 | 1687 | 486 | 3081 | 6.34 | 440.1 |
| 3 | Connecticut | 3 | 278 | 550 | 197 | 828 | 4.20 | 276.0 |
| 4 | Massachusetts | 3 | 275 | 510 | 178 | 785 | 4.41 | 261.7 |
| 5 | Liberty | 2 | 434 | 392 | 143 | 826 | 5.78 | 413.0 |
| 6 | Army | 3 | 806 | 361 | 203 | 1167 | 5.75 | 389.0 |
| 7 | New Mexico State | 2 | 110 | 310 | 119 | 420 | 3.53 | 210.0 |