2021 Independent Leaders Total Defense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Army | 12 | 1351 | 2287 | 689 | 3638 | 5.28 | 303.2 |
| 2 | Liberty | 11 | 1547 | 1854 | 754 | 3401 | 4.51 | 309.2 |
| 3 | Notre Dame | 11 | 1434 | 2247 | 730 | 3681 | 5.04 | 334.6 |
| 4 | BYU | 10 | 1515 | 2323 | 672 | 3838 | 5.71 | 383.8 |
| 5 | Connecticut | 10 | 2048 | 2426 | 751 | 4474 | 5.96 | 447.4 |
| 6 | New Mexico State | 8 | 1493 | 2259 | 524 | 3752 | 7.16 | 469.0 |
| 7 | Massachusetts | 11 | 2602 | 2620 | 708 | 5222 | 7.38 | 474.7 |