2021 Pac-12 Conference Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | USC | 3 | 34 | 37 | 4 | 75 | 25.0 |
| 2 | Arizona State | 2 | 26 | 21 | 1 | 48 | 24.0 |
| 3 | Oregon State | 2 | 24 | 23 | 4 | 51 | 25.5 |
| 4 | UCLA | 2 | 19 | 17 | 1 | 37 | 18.5 |
| 5 | Washington State | 3 | 14 | 30 | 7 | 51 | 17.0 |
| 6 | Arizona | 2 | 12 | 20 | 4 | 36 | 18.0 |
| 7 | Washington | 1 | 10 | 17 | 3 | 30 | 30.0 |
| 7 | Oregon | 1 | 10 | 7 | 4 | 21 | 21.0 |
| 7 | Utah | 2 | 10 | 20 | 6 | 36 | 18.0 |
| 10 | California | 1 | 8 | 7 | 2 | 17 | 17.0 |
| 11 | Stanford | 1 | 5 | 5 | 1 | 11 | 11.0 |