2021 Pac-12 Conference Leaders First Downs - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Oregon | 4 | 45 | 44 | 11 | 100 | 25.0 |
| 1 | Arizona State | 4 | 45 | 33 | 5 | 83 | 20.8 |
| 3 | Oregon State | 4 | 43 | 42 | 4 | 89 | 22.3 |
| 4 | USC | 3 | 34 | 37 | 4 | 75 | 25.0 |
| 5 | UCLA | 3 | 31 | 24 | 1 | 56 | 18.7 |
| 6 | Utah | 4 | 30 | 46 | 13 | 89 | 22.3 |
| 7 | California | 3 | 28 | 28 | 6 | 62 | 20.7 |
| 7 | Colorado | 3 | 28 | 11 | 3 | 42 | 14.0 |
| 9 | Washington State | 4 | 25 | 45 | 8 | 78 | 19.5 |
| 10 | Arizona | 3 | 20 | 30 | 5 | 55 | 18.3 |
| 11 | Washington | 3 | 19 | 43 | 8 | 70 | 23.3 |
| 12 | Stanford | 3 | 15 | 24 | 6 | 45 | 15.0 |