2021 Pac-12 Conference Leaders Passes Defended - Games in August/September Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oregon State | 4 | 8 | 23 | 31 | 7.75 |
| 2 | California | 4 | 3 | 17 | 20 | 5.00 |
| 3 | Stanford | 4 | 3 | 16 | 19 | 4.75 |
| 4 | UCLA | 4 | 4 | 15 | 19 | 4.75 |
| 4 | Washington State | 4 | 4 | 15 | 19 | 4.75 |
| 4 | Arizona | 4 | 2 | 15 | 17 | 4.25 |
| 7 | Washington | 4 | 3 | 14 | 17 | 4.25 |
| 8 | Utah | 4 | 4 | 13 | 17 | 4.25 |
| 9 | Arizona State | 4 | 5 | 12 | 17 | 4.25 |
| 10 | Colorado | 4 | 1 | 11 | 12 | 3.00 |
| 11 | Oregon | 4 | 9 | 6 | 15 | 3.75 |
| 11 | USC | 4 | 6 | 6 | 12 | 3.00 |