2021 Pac-12 Conference Leaders Total Defense - Games in November Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Washington State | 3 | 484 | 531 | 186 | 1015 | 5.46 | 338.3 |
| 2 | California | 3 | 522 | 532 | 223 | 1054 | 4.73 | 351.3 |
| 3 | Washington | 4 | 895 | 545 | 274 | 1440 | 5.26 | 360.0 |
| 4 | UCLA | 3 | 443 | 616 | 225 | 1059 | 4.71 | 353.0 |
| 5 | Utah | 4 | 313 | 627 | 232 | 940 | 4.05 | 235.0 |
| 6 | Oregon State | 4 | 689 | 705 | 243 | 1394 | 5.74 | 348.5 |
| 7 | Arizona | 4 | 653 | 733 | 237 | 1386 | 5.85 | 346.5 |
| 8 | USC | 3 | 709 | 770 | 202 | 1479 | 7.32 | 493.0 |
| 9 | Arizona State | 4 | 474 | 827 | 272 | 1301 | 4.78 | 325.3 |
| 10 | Oregon | 4 | 439 | 877 | 240 | 1316 | 5.48 | 329.0 |
| 11 | Stanford | 4 | 1180 | 1014 | 278 | 2194 | 7.89 | 548.5 |
| 12 | Colorado | 4 | 767 | 1079 | 300 | 1846 | 6.15 | 461.5 |