2021 Mid-American Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Kent State | 3 | 5 | 7 | 12 | 4.00 |
| 2 | Central Michigan | 3 | 1 | 9 | 10 | 3.33 |
| 3 | Bowling Green | 2 | 2 | 5 | 7 | 3.50 |
| 4 | Miami (Ohio) | 1 | 0 | 6 | 6 | 6.00 |
| 5 | Western Michigan | 2 | 1 | 4 | 5 | 2.50 |
| 6 | Eastern Michigan | 1 | 1 | 2 | 3 | 3.00 |
| 6 | Northern Illinois | 2 | 0 | 3 | 3 | 1.50 |
| 8 | Ball State | 1 | 0 | 2 | 2 | 2.00 |
| 8 | Akron | 2 | 1 | 1 | 2 | 1.00 |
| 8 | Ohio | 2 | 0 | 2 | 2 | 1.00 |
| 11 | Buffalo | 1 | 0 | 1 | 1 | 1.00 |