2021 Mid-American Conference Leaders Sacks - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Central Michigan | 13 | 42.0 | 303 | 3.23 |
| 2 | Western Michigan | 11 | 40.0 | 257 | 3.64 |
| 3 | Buffalo | 12 | 36.0 | 244 | 3.00 |
| 3 | Miami (Ohio) | 12 | 36.0 | 241 | 3.00 |
| 5 | Toledo | 12 | 33.0 | 202 | 2.75 |
| 6 | Bowling Green | 12 | 28.0 | 181 | 2.33 |
| 7 | Eastern Michigan | 13 | 24.0 | 159 | 1.85 |
| 8 | Kent State | 13 | 23.0 | 156 | 1.77 |
| 8 | Ball State | 13 | 23.0 | 137 | 1.77 |
| 10 | Northern Illinois | 13 | 19.0 | 123 | 1.46 |
| 11 | Ohio | 11 | 16.0 | 101 | 1.46 |
| 12 | Akron | 11 | 13.0 | 118 | 1.18 |