2021 Mid-American Conference Leaders Rushing Offense - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (Ohio) | 1 | 45 | 169 | 3.76 | 1 | 45.00 | 169.00 |
| 2 | Kent State | 1 | 41 | 80 | 1.95 | 0 | 41.00 | 80.00 |
| 3 | Western Michigan | 2 | 80 | 286 | 3.58 | 4 | 40.00 | 143.00 |
| 3 | Akron | 1 | 40 | 76 | 1.90 | 0 | 40.00 | 76.00 |
| 5 | Northern Illinois | 1 | 36 | 161 | 4.47 | 0 | 36.00 | 161.00 |
| 6 | Toledo | 1 | 30 | 124 | 4.13 | 1 | 30.00 | 124.00 |
| 7 | Ohio | 1 | 28 | 112 | 4.00 | 0 | 28.00 | 112.00 |