2021 Mid-American Conference Leaders Total Offense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Kent State | 5 | 1269 | 1144 | 378 | 2413 | 6.38 | 482.6 |
| 2 | Central Michigan | 5 | 866 | 1363 | 399 | 2229 | 5.59 | 445.8 |
| 3 | Western Michigan | 5 | 1018 | 1084 | 364 | 2102 | 5.77 | 420.4 |
| 4 | Northern Illinois | 5 | 1197 | 878 | 343 | 2075 | 6.05 | 415.0 |
| 5 | Toledo | 5 | 805 | 1179 | 333 | 1984 | 5.96 | 396.8 |
| 6 | Eastern Michigan | 5 | 788 | 1099 | 346 | 1887 | 5.45 | 377.4 |
| 7 | Miami (Ohio) | 5 | 733 | 1074 | 320 | 1807 | 5.65 | 361.4 |
| 8 | Ball State | 5 | 513 | 1082 | 349 | 1595 | 4.57 | 319.0 |
| 9 | Buffalo | 4 | 752 | 822 | 293 | 1574 | 5.37 | 393.5 |
| 10 | Akron | 4 | 462 | 831 | 274 | 1293 | 4.72 | 323.3 |
| 11 | Ohio | 4 | 564 | 687 | 227 | 1251 | 5.51 | 312.8 |
| 12 | Bowling Green | 4 | 181 | 886 | 245 | 1067 | 4.36 | 266.8 |