2021 Mid-American Conference Leaders Passing Defense - Games in December/January Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 1 | 23 | 12 | 52.2 | 121 | 5.3 | 1 | 1 | 102.01 | 23.0 | 121.0 |
| 2 | Central Michigan | 1 | 40 | 18 | 45.0 | 227 | 5.7 | 2 | 0 | 109.17 | 40.0 | 227.0 |
| 3 | Toledo | 1 | 41 | 24 | 58.5 | 276 | 6.7 | 2 | 1 | 126.31 | 41.0 | 276.0 |
| 4 | Miami (Ohio) | 1 | 32 | 15 | 46.9 | 228 | 7.1 | 0 | 2 | 94.23 | 32.0 | 228.0 |
| 5 | Kent State | 2 | 26 | 16 | 61.5 | 229 | 8.8 | 1 | 1 | 140.53 | 13.0 | 114.5 |
| 6 | Northern Illinois | 2 | 56 | 38 | 67.9 | 511 | 9.1 | 6 | 2 | 172.73 | 28.0 | 255.5 |
| 7 | Ball State | 1 | 21 | 17 | 81.0 | 205 | 9.8 | 3 | 0 | 210.09 | 21.0 | 205.0 |
| 8 | Eastern Michigan | 1 | 26 | 14 | 53.8 | 295 | 11.3 | 4 | 1 | 192.24 | 26.0 | 295.0 |