2021 Mid-American Conference Leaders Passing Defense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Bowling Green | 4 | 111 | 59 | 53.2 | 592 | 5.3 | 1 | 5 | 91.91 | 27.8 | 148.0 |
| 2 | Ohio | 4 | 106 | 72 | 67.9 | 634 | 6.0 | 3 | 1 | 125.62 | 26.5 | 158.5 |
| 3 | Toledo | 5 | 149 | 79 | 53.0 | 948 | 6.4 | 7 | 5 | 115.25 | 29.8 | 189.6 |
| 4 | Western Michigan | 5 | 119 | 67 | 56.3 | 840 | 7.1 | 10 | 4 | 136.61 | 23.8 | 168.0 |
| 5 | Kent State | 5 | 159 | 104 | 65.4 | 1161 | 7.3 | 7 | 9 | 129.96 | 31.8 | 232.2 |
| 6 | Miami (Ohio) | 5 | 101 | 58 | 57.4 | 813 | 8.0 | 7 | 4 | 140.00 | 20.2 | 162.6 |
| 7 | Ball State | 5 | 133 | 88 | 66.2 | 1092 | 8.2 | 8 | 3 | 150.48 | 26.6 | 218.4 |
| 7 | Eastern Michigan | 5 | 140 | 83 | 59.3 | 1145 | 8.2 | 9 | 4 | 143.50 | 28.0 | 229.0 |
| 9 | Central Michigan | 5 | 161 | 95 | 59.0 | 1334 | 8.3 | 11 | 2 | 148.68 | 32.2 | 266.8 |
| 10 | Northern Illinois | 5 | 123 | 77 | 62.6 | 1075 | 8.7 | 8 | 0 | 157.48 | 24.6 | 215.0 |
| 11 | Buffalo | 4 | 94 | 57 | 60.6 | 828 | 8.8 | 6 | 2 | 151.44 | 23.5 | 207.0 |
| 12 | Akron | 4 | 101 | 76 | 75.2 | 1054 | 10.4 | 8 | 1 | 187.07 | 25.3 | 263.5 |