2021 Mid-American Conference Leaders Passing Defense - Games in November Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 4 | 96 | 56 | 58.3 | 746 | 7.8 | 5 | 0 | 140.80 | 24.0 | 186.5 |
| 2 | Akron | 4 | 101 | 60 | 59.4 | 769 | 7.6 | 9 | 1 | 150.80 | 25.3 | 192.3 |
| 3 | Bowling Green | 3 | 69 | 40 | 58.0 | 600 | 8.7 | 5 | 4 | 143.34 | 23.0 | 200.0 |
| 4 | Toledo | 4 | 135 | 78 | 57.8 | 855 | 6.3 | 8 | 2 | 127.58 | 33.8 | 213.8 |
| 5 | Northern Illinois | 4 | 105 | 68 | 64.8 | 948 | 9.0 | 9 | 0 | 168.88 | 26.3 | 237.0 |
| 6 | Buffalo | 3 | 86 | 57 | 66.3 | 724 | 8.4 | 5 | 0 | 156.19 | 28.7 | 241.3 |
| 7 | Miami (Ohio) | 4 | 129 | 80 | 62.0 | 978 | 7.6 | 6 | 3 | 136.40 | 32.3 | 244.5 |
| 8 | Central Michigan | 4 | 148 | 95 | 64.2 | 989 | 6.7 | 4 | 2 | 126.54 | 37.0 | 247.3 |
| 9 | Ball State | 4 | 135 | 86 | 63.7 | 1015 | 7.5 | 5 | 7 | 128.71 | 33.8 | 253.8 |
| 10 | Eastern Michigan | 4 | 119 | 74 | 62.2 | 1105 | 9.3 | 9 | 3 | 160.11 | 29.8 | 276.3 |
| 11 | Ohio | 4 | 165 | 107 | 64.8 | 1251 | 7.6 | 8 | 2 | 142.12 | 41.3 | 312.8 |
| 12 | Kent State | 4 | 157 | 95 | 60.5 | 1332 | 8.5 | 11 | 2 | 152.35 | 39.3 | 333.0 |