2021 Mid-American Conference Leaders Scoring Defense - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Kent State | 1 | 4 | 0 | 4 | 0 | 1 | 30 | 30.0 |
| 2 | Toledo | 1 | 4 | 1 | 3 | 1 | 0 | 32 | 32.0 |
| 3 | Miami (Ohio) | 1 | 7 | 0 | 7 | 0 | 0 | 49 | 49.0 |
| 3 | Ohio | 1 | 7 | 0 | 7 | 0 | 0 | 49 | 49.0 |
| 5 | Akron | 1 | 8 | 1 | 8 | 0 | 0 | 59 | 59.0 |
| 6 | Northern Illinois | 1 | 9 | 0 | 9 | 0 | 0 | 63 | 63.0 |
| 7 | Western Michigan | 2 | 12 | 2 | 10 | 0 | 0 | 88 | 44.0 |