2021 Mid-American Conference Leaders Rushing Defense - From Opponent's 21 To 39 Yard Line through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Ohio | 12 | 109 | 514 | 4.72 | 0 | 58 | 25 | 14 | 4 |
| 2 | Western Michigan | 13 | 127 | 569 | 4.48 | 1 | 74 | 30 | 20 | 7 |
| 3 | Akron | 12 | 134 | 895 | 6.68 | 0 | 62 | 43 | 29 | 6 |
| 4 | Northern Illinois | 14 | 135 | 972 | 7.20 | 1 | 66 | 46 | 32 | 13 |
| 5 | Kent State | 14 | 137 | 738 | 5.39 | 2 | 64 | 35 | 19 | 6 |
| 6 | Bowling Green | 12 | 146 | 454 | 3.11 | 0 | 39 | 28 | 13 | 1 |
| 7 | Ball State | 13 | 148 | 798 | 5.39 | 2 | 70 | 38 | 20 | 5 |
| 7 | Miami (Ohio) | 13 | 148 | 839 | 5.67 | 4 | 79 | 37 | 16 | 9 |
| 9 | Central Michigan | 13 | 154 | 492 | 3.19 | 0 | 46 | 34 | 22 | 6 |
| 10 | Eastern Michigan | 13 | 155 | 918 | 5.92 | 1 | 67 | 46 | 29 | 7 |
| 11 | Buffalo | 12 | 162 | 916 | 5.65 | 3 | 77 | 39 | 29 | 9 |
| 12 | Toledo | 13 | 180 | 543 | 3.02 | 0 | 50 | 31 | 13 | 4 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||