2021 Mid-American Conference Leaders Rushing Defense - In The 2nd Quarter through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Central Michigan | 13 | 127 | 360 | 2.83 | 2 | 40 | 23 | 15 | 2 |
| 2 | Western Michigan | 13 | 102 | 621 | 6.09 | 3 | 96 | 28 | 21 | 9 |
| 3 | Miami (Ohio) | 13 | 129 | 510 | 3.95 | 5 | 75 | 24 | 12 | 5 |
| 4 | Ohio | 12 | 122 | 580 | 4.75 | 6 | 36 | 35 | 22 | 3 |
| 4 | Toledo | 13 | 146 | 641 | 4.39 | 6 | 43 | 35 | 25 | 6 |
| 4 | Buffalo | 12 | 137 | 661 | 4.82 | 6 | 75 | 36 | 21 | 7 |
| 7 | Kent State | 14 | 147 | 550 | 3.74 | 7 | 50 | 36 | 14 | 1 |
| 7 | Eastern Michigan | 13 | 129 | 735 | 5.70 | 7 | 82 | 38 | 22 | 5 |
| 9 | Bowling Green | 12 | 136 | 493 | 3.63 | 9 | 39 | 31 | 13 | 4 |
| 9 | Akron | 12 | 127 | 701 | 5.52 | 9 | 29 | 48 | 27 | 4 |
| 11 | Northern Illinois | 14 | 125 | 732 | 5.86 | 10 | 49 | 38 | 23 | 9 |
| 12 | Ball State | 13 | 139 | 707 | 5.09 | 13 | 70 | 37 | 20 | 6 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||