2021 Mid-American Conference Leaders Long All Purpose Plays - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Matt Landers | Toledo | JR | WR | 11 | 5 | 4 | 3 | 3 | 3 | 3 | 1 |
| 2 | Jack Sorenson | Miami (Oh) | SR | WR | 12 | 11 | 6 | 5 | 2 | 2 | 2 | 0 |
| 2 | Sean Tyler | W Mich | SO | RB | 11 | 7 | 4 | 4 | 4 | 3 | 2 | 2 |
| 4 | David Carter Jr. | EMU | FR | DB | 13 | 2 | 2 | 1 | 1 | 1 | 1 | 1 |
| 4 | Dante Cephas | Kent State | SO | WR | 13 | 10 | 8 | 3 | 1 | 1 | 1 | 0 |
| 4 | Kevin Davis | Miami (Oh) | FR | RB | 12 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 4 | Justin Hall | Ball State | SR | WR | 11 | 10 | 4 | 2 | 2 | 2 | 1 | 1 |
| 4 | Marion Lukes | CMU | FR | RB | 13 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 4 | Devin Maddox | Toledo | SO | WR | 12 | 4 | 2 | 2 | 2 | 1 | 1 | 0 |
| 4 | Michael Mathison | Akron | SO | WR | 10 | 7 | 2 | 2 | 1 | 1 | 1 | 1 |
| 4 | Kalil Pimpleton | CMU | JR | WR | 13 | 11 | 7 | 4 | 3 | 3 | 1 | 1 |
| 4 | Clint Ratkovich | N Illinois | SR | RB | 13 | 2 | 2 | 2 | 1 | 1 | 1 | 1 |
| 4 | Armani Rogers | Ohio | SR | QB | 11 | 2 | 2 | 2 | 1 | 1 | 1 | 1 |
| 4 | Trayvon Rudolph | N Illinois | FR | WR | 13 | 16 | 7 | 4 | 4 | 4 | 1 | 1 |
| 4 | Christian Sims | BGSU | JR | TE | 11 | 2 | 2 | 2 | 1 | 1 | 1 | 0 |
| 4 | Jacquez Stuart | Toledo | FR | RB | 12 | 4 | 2 | 1 | 1 | 1 | 1 | 1 |
| 4 | De'Montre Tuggle | Ohio | SR | RB | 11 | 7 | 5 | 2 | 2 | 1 | 1 | 0 |