2021 Big Ten Conference Leaders Total Offense - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Purdue | 2 | 244 | 666 | 157 | 910 | 5.80 | 455.0 |
| 2 | Indiana | 2 | 286 | 597 | 169 | 883 | 5.22 | 441.5 |
| 3 | Ohio State | 2 | 560 | 570 | 127 | 1130 | 8.90 | 565.0 |
| 4 | Wisconsin | 3 | 628 | 518 | 202 | 1146 | 5.67 | 382.0 |
| 5 | Michigan | 2 | 708 | 449 | 125 | 1157 | 9.26 | 578.5 |
| 6 | Iowa | 2 | 260 | 436 | 130 | 696 | 5.35 | 348.0 |
| 7 | Maryland | 1 | 142 | 384 | 69 | 526 | 7.62 | 526.0 |
| 8 | Illinois | 2 | 486 | 344 | 147 | 830 | 5.65 | 415.0 |
| 9 | Michigan State | 1 | 192 | 327 | 73 | 519 | 7.11 | 519.0 |
| 10 | Nebraska | 1 | 220 | 296 | 61 | 516 | 8.46 | 516.0 |
| 11 | Penn State | 1 | 240 | 253 | 79 | 493 | 6.24 | 493.0 |
| 12 | Minnesota | 2 | 357 | 171 | 120 | 528 | 4.40 | 264.0 |
| 13 | Rutgers | 1 | 220 | 145 | 80 | 365 | 4.56 | 365.0 |
| 14 | Northwestern | 1 | 373 | 88 | 71 | 461 | 6.49 | 461.0 |