2021 Big Ten Conference Leaders Total Offense - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Ohio State | 11 | 1784 | 4382 | 790 | 6166 | 7.81 | 560.5 |
| 2 | Purdue | 11 | 848 | 3950 | 810 | 4798 | 5.92 | 436.2 |
| 3 | Maryland | 11 | 1405 | 3229 | 778 | 4634 | 5.96 | 421.3 |
| 4 | Penn State | 11 | 1084 | 2809 | 779 | 3893 | 5.00 | 353.9 |
| 5 | Michigan | 12 | 2293 | 2753 | 845 | 5046 | 5.97 | 420.5 |
| 6 | Michigan State | 11 | 1819 | 2648 | 740 | 4467 | 6.04 | 406.1 |
| 7 | Nebraska | 10 | 1613 | 2597 | 676 | 4210 | 6.23 | 421.0 |
| 8 | Iowa | 12 | 1471 | 2085 | 781 | 3556 | 4.55 | 296.3 |
| 9 | Northwestern | 10 | 1109 | 1974 | 684 | 3083 | 4.51 | 308.3 |
| 10 | Minnesota | 11 | 2217 | 1935 | 738 | 4152 | 5.63 | 377.5 |
| 11 | Rutgers | 11 | 1434 | 1754 | 747 | 3188 | 4.27 | 289.8 |
| 12 | Wisconsin | 10 | 2114 | 1564 | 665 | 3678 | 5.53 | 367.8 |
| 13 | Illinois | 10 | 1597 | 1530 | 643 | 3127 | 4.86 | 312.7 |
| 14 | Indiana | 9 | 905 | 1350 | 579 | 2255 | 3.89 | 250.6 |