2021 Big Ten Conference Leaders Opponent First Downs - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Minnesota | 6 | 35 | 61 | 12 | 108 | 18.0 |
| 2 | Wisconsin | 9 | 36 | 68 | 10 | 114 | 12.7 |
| 3 | Northwestern | 6 | 67 | 67 | 9 | 143 | 23.8 |
| 4 | Illinois | 7 | 69 | 71 | 8 | 148 | 21.1 |
| 5 | Maryland | 6 | 64 | 76 | 15 | 155 | 25.8 |
| 6 | Purdue | 8 | 67 | 75 | 14 | 156 | 19.5 |
| 7 | Michigan | 9 | 64 | 86 | 9 | 159 | 17.7 |
| 8 | Iowa | 8 | 63 | 84 | 14 | 161 | 20.1 |
| 9 | Rutgers | 7 | 74 | 78 | 11 | 163 | 23.3 |
| 10 | Nebraska | 8 | 65 | 87 | 12 | 164 | 20.5 |
| 11 | Penn State | 7 | 78 | 71 | 16 | 165 | 23.6 |
| 12 | Michigan State | 8 | 53 | 140 | 16 | 209 | 26.1 |
| 13 | Ohio State | 9 | 74 | 120 | 20 | 214 | 23.8 |
| 14 | Indiana | 10 | 82 | 120 | 18 | 220 | 22.0 |