2021 Big Ten Conference Leaders Rushing Defense - From Opponent's 21 To 39 Yard Line through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 13 | 141 | 325 | 2.30 | 0 | 34 | 20 | 10 | 4 |
| 1 | Indiana | 12 | 110 | 489 | 4.45 | 0 | 62 | 23 | 15 | 5 |
| 1 | Michigan State | 13 | 140 | 512 | 3.66 | 0 | 49 | 28 | 13 | 6 |
| 1 | Rutgers | 13 | 158 | 659 | 4.17 | 0 | 71 | 37 | 20 | 8 |
| 1 | Purdue | 13 | 152 | 719 | 4.73 | 0 | 60 | 37 | 19 | 8 |
| 1 | Penn State | 13 | 174 | 849 | 4.88 | 0 | 68 | 44 | 32 | 6 |
| 7 | Minnesota | 13 | 141 | 504 | 3.57 | 1 | 71 | 28 | 18 | 3 |
| 7 | Illinois | 12 | 137 | 520 | 3.80 | 1 | 75 | 30 | 13 | 3 |
| 7 | Iowa | 14 | 154 | 567 | 3.68 | 1 | 67 | 31 | 16 | 3 |
| 7 | Michigan | 14 | 189 | 654 | 3.46 | 1 | 75 | 29 | 16 | 6 |
| 7 | Northwestern | 12 | 129 | 711 | 5.51 | 1 | 75 | 26 | 13 | 6 |
| 7 | Nebraska | 12 | 133 | 801 | 6.02 | 1 | 71 | 37 | 16 | 8 |
| 13 | Maryland | 13 | 149 | 662 | 4.44 | 2 | 66 | 37 | 21 | 5 |
| 13 | Ohio State | 13 | 168 | 689 | 4.10 | 2 | 77 | 35 | 24 | 6 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||