2021 Big Ten Conference Leaders Interceptions - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Ronnie Hickman | Ohio State | SO | SAF | 2 | 2 | 65 | 1 | 1.00 |
| 1 | Max Melton | Rutgers | FR | DB | 1 | 1 | 46 | 1 | 1.00 |
| 1 | Jesse Luketa | Penn State | SR | DE | 1 | 1 | 16 | 1 | 1.00 |
| 1 | Cameron Martinez | Ohio State | FR | SAF | 2 | 1 | 61 | 1 | 0.50 |