2021 Big Ten Conference Leaders Interceptions - Games at Home Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Riley Moss | Iowa | SR | DB | 6 | 3 | 85 | 2 | 0.50 |
| 2 | Craig Young | Ohio State | SO | SAF | 7 | 2 | 88 | 1 | 0.29 |
| 2 | Ronnie Hickman | Ohio State | SO | SAF | 7 | 2 | 65 | 1 | 0.29 |
| 2 | Max Melton | Rutgers | FR | DB | 4 | 1 | 46 | 1 | 0.25 |
| 2 | Cameron Martinez | Ohio State | FR | SAF | 6 | 1 | 61 | 1 | 0.17 |
| 2 | Jack Campbell | Iowa | JR | LB | 7 | 1 | 32 | 1 | 0.14 |
| 2 | Jesse Luketa | Penn State | SR | DE | 7 | 1 | 16 | 1 | 0.14 |