2021 Big Ten Conference Leaders Long Scrimmage Plays - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Braelon Allen | Wisconsin | FR | RB | 10 | 29 | 13 | 8 | 4 | 3 | 2 | 2 | 0 | 0 |
| 1 | Broc Thompson | Purdue | JR | WR | 11 | 11 | 4 | 3 | 2 | 2 | 2 | 2 | 0 | 0 |
| 1 | Samori Toure | Nebraska | SR | WR | 10 | 23 | 10 | 6 | 4 | 3 | 2 | 2 | 0 | 0 |
| 1 | Kenneth Walker III | Mich St | JR | RB | 10 | 46 | 20 | 8 | 4 | 4 | 2 | 2 | 1 | 1 |
| 5 | Andrel Anthony | Michigan | FR | WR | 9 | 9 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 5 | Zavier Betts | Nebraska | FR | WR | 10 | 10 | 5 | 3 | 2 | 2 | 1 | 1 | 1 | 0 |
| 5 | Aron Cruickshank | Rutgers | JR | WR | 5 | 6 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Danny Davis III | Wisconsin | SR | WR | 9 | 15 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Jahan Dotson | Penn State | SR | WR | 10 | 39 | 14 | 9 | 4 | 1 | 1 | 1 | 1 | 0 |
| 5 | Donovan Edwards | Michigan | FR | RB | 10 | 8 | 3 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 5 | TreVeyon Henderson | Ohio State | FR | RB | 11 | 37 | 12 | 5 | 4 | 3 | 2 | 1 | 0 | 0 |
| 5 | Evan Hull | N'western | SO | RB | 10 | 26 | 6 | 5 | 2 | 1 | 1 | 1 | 0 | 0 |
| 5 | Charlie Jones | Iowa | SR | WR | 12 | 12 | 5 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Darryl Jones | Maryland | SR | WR | 11 | 9 | 7 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Adrian Martinez | Nebraska | JR | QB | 9 | 13 | 6 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 5 | Jaxon Smith-Njigba | Ohio State | SO | WR | 11 | 55 | 25 | 12 | 8 | 5 | 1 | 1 | 0 | 0 |
| 5 | Miyan Williams | Ohio State | FR | RB | 9 | 19 | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Garrett Wilson | Ohio State | JR | WR | 9 | 37 | 14 | 4 | 3 | 3 | 1 | 1 | 0 | 0 |
| 5 | Roman Wilson | Michigan | SO | WR | 11 | 11 | 8 | 5 | 2 | 1 | 1 | 1 | 0 | 0 |