2021 Big Ten Conference Leaders Long All Purpose Plays - Games vs. FCS (I-AA) Teams Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Jayden Reed | Mich St | JR | WR | 1 | 4 | 2 | 2 | 2 | 2 | 1 | 0 |
| 1 | Parker Washington | Penn State | SO | WR | 1 | 2 | 2 | 2 | 1 | 0 | 0 | 0 |
| 3 | AJ Barner | Indiana | SO | TE | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Aron Cruickshank | Rutgers | JR | WR | 1 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | Jahan Dotson | Penn State | SR | WR | 1 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Jacolby Hewitt | Indiana | JR | WR | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Brandon Joseph | N'western | SO | SAF | 1 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 3 | KeAndre Lambert-Smith | Penn State | SO | WR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | D.J. Matthews Jr. | Indiana | SR | WR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | Bo Melton | Rutgers | SR | WR | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Brandon Sanders | Rutgers | SR | WR | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |