2021 American Athletic Conference Leaders Time Of Possession - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Total Time | Time/G | |
|---|---|---|---|---|
| 1 | SMU | 1 | 33:52 | 33:52.00 |
| 2 | Houston | 2 | 66:27 | 33:13.50 |
| 3 | Tulsa | 2 | 63:07 | 31:33.50 |
| 4 | UCF | 2 | 62:03 | 31:01.50 |
| 5 | South Florida | 2 | 60:06 | 30:03.00 |
| 6 | East Carolina | 1 | 28:59 | 28:59.00 |
| 7 | Cincinnati | 2 | 56:18 | 28:09.00 |
| 8 | Tulane | 2 | 54:20 | 27:10.00 |
| 9 | Temple | 2 | 51:09 | 25:34.50 |
| 10 | Memphis | 1 | 23:03 | 23:03.00 |