2021 American Athletic Conference Leaders Total Offense - Games Lost Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tulane | 10 | 1493 | 2060 | 681 | 3553 | 5.22 | 355.3 |
| 2 | South Florida | 10 | 1236 | 2041 | 675 | 3277 | 4.85 | 327.7 |
| 3 | Temple | 9 | 866 | 1257 | 522 | 2123 | 4.07 | 235.9 |
| 4 | Navy | 8 | 1653 | 469 | 520 | 2122 | 4.08 | 265.3 |
| 5 | Memphis | 6 | 677 | 1761 | 440 | 2438 | 5.54 | 406.3 |
| 6 | Tulsa | 6 | 900 | 1437 | 414 | 2337 | 5.64 | 389.5 |
| 7 | East Carolina | 5 | 479 | 1172 | 348 | 1651 | 4.74 | 330.2 |
| 8 | SMU | 4 | 351 | 931 | 258 | 1282 | 4.97 | 320.5 |
| 9 | UCF | 4 | 639 | 732 | 249 | 1371 | 5.51 | 342.8 |
| 10 | Houston | 2 | 163 | 424 | 146 | 587 | 4.02 | 293.5 |
| 11 | Cincinnati | 1 | 74 | 144 | 58 | 218 | 3.76 | 218.0 |