2021 American Athletic Conference Leaders Total Offense - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 8 | 1357 | 2278 | 550 | 3635 | 6.61 | 454.4 |
| 2 | SMU | 7 | 1235 | 2276 | 522 | 3511 | 6.73 | 501.6 |
| 3 | Tulsa | 7 | 1595 | 1728 | 530 | 3323 | 6.27 | 474.7 |
| 4 | East Carolina | 5 | 1150 | 1448 | 401 | 2598 | 6.48 | 519.6 |
| 5 | UCF | 8 | 1563 | 1437 | 500 | 3000 | 6.00 | 375.0 |
| 6 | Memphis | 4 | 676 | 1273 | 270 | 1949 | 7.22 | 487.3 |
| 7 | Cincinnati | 5 | 818 | 1180 | 327 | 1998 | 6.11 | 399.6 |
| 8 | Temple | 6 | 657 | 1167 | 348 | 1824 | 5.24 | 304.0 |
| 9 | South Florida | 3 | 653 | 467 | 241 | 1120 | 4.65 | 373.3 |
| 10 | Tulane | 2 | 495 | 458 | 137 | 953 | 6.96 | 476.5 |
| 11 | Navy | 2 | 416 | 115 | 143 | 531 | 3.71 | 265.5 |