2021 American Athletic Conference Leaders Total Offense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 9 | 1755 | 2170 | 557 | 3925 | 7.05 | 436.1 |
| 2 | Houston | 9 | 1343 | 2515 | 626 | 3858 | 6.16 | 428.7 |
| 3 | East Carolina | 8 | 1427 | 2173 | 621 | 3600 | 5.80 | 450.0 |
| 4 | SMU | 8 | 1008 | 2384 | 585 | 3392 | 5.80 | 424.0 |
| 5 | Memphis | 8 | 895 | 2415 | 596 | 3310 | 5.55 | 413.8 |
| 6 | Tulsa | 8 | 1501 | 1750 | 577 | 3251 | 5.63 | 406.4 |
| 7 | Tulane | 8 | 1354 | 1604 | 529 | 2958 | 5.59 | 369.8 |
| 8 | South Florida | 8 | 1270 | 1605 | 561 | 2875 | 5.12 | 359.4 |
| 9 | UCF | 8 | 1227 | 1372 | 489 | 2599 | 5.31 | 324.9 |
| 10 | Navy | 8 | 1982 | 488 | 542 | 2470 | 4.56 | 308.8 |
| 11 | Temple | 8 | 832 | 1270 | 482 | 2102 | 4.36 | 262.8 |